Mobile Phases for Chromatography

Analytical HPLC has a central role in research and development, pharmaceutical quality control, and environmental
analysis.
 


LiChrosolv® Solvents for Liquid Chromatography

For more accurate results in HPLC and TLC, it is vital that solvents offer high purity, low UV absorption, low particle count, low acidity and alkalinity combined with low evaporation residue. These requirements are ideally fulfilled by Merck Millipore’s LiChrosolv® solvents. These are produced from specially-selected raw materials that are purified through a multi-step process. LiChrosolv® HPLC solvents offer batch-to-batch consistency, and no trace impurities, and therefore prevent inaccurate results when using UV or fluorescence detectors

LiChrosolv® Hypergrade Solvents for LC-MS
The combination of classical liquid chromatography (LC) with mass spectrometry (MS) has become the dominant analytical tool for researchers in almost every chemical analysis field. LC-MS combines the advantages of chromatographic separation with mass detection by MS. This results in low detection limits, enabling the successful analysis of molecular structures, such as molecular identification and characterization. Our LiChrosolv® hypergrade solvents were developed specially for LC-MS, including very high UV-transfer with very low metal ion content and optimal LC-MS background signal noise ratio. In addition, the quality of the solvents ensures optimum chromatographic results and prevents the loss of valuable samples.

Prepsolv® Solvents for Preparative Chromatography


Prepsolv® solvents are designed to complement a variety of solvents from scale-up to preparative separations. Thanks to their special characteristics, such as low evaporation residue, Prepsolv® solvents ensure optimum product yield and column protection.

LiChropur® Reagents for Analytical HPLC

LiChropur® reagents are manufactured to ensure high UV-transmittance, even at wavelengths too low to detect. Hydrophobic ionic compounds comprise neutral ion pairs with oppositely charged sample molecules. In this way, the simultaneous separation of charged and non-charged molecules is made possible.